HEPATOCYTE ISOLATION AND EX VIVO HEPATOPROTECTION OF ORTHOSIPHON ARISTATUS EXTRACT ON CARBON TETRACHLORIDE INDUCED HEPATOTOXICITY
نویسندگان
چکیده
منابع مشابه
Effect of propolis extract on acute carbon tetrachloride induced hepatotoxicity.
Ethanolic extract of propolis was administered to rats intoxicated by carbon tetrachloride. Administration of bolus dose of CCl4 (1.5 ml/kg, ip) resulted in elevation of serum transaminases and serum alkaline phosphatase activities. Levels of hepatic lipid peroxidation were significantly increased. On the contrary, there was significant decrease in hepatic reduced glutathione level. The propoli...
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Oxidizing agents play a major role in the pathogenesis of liver diseases. Pistacia vera (P. vera), contains many antioxidant substances including coenzyme 10, vitamin E and beta-carotene. The current study was designed to evaluate the probable effects of P. vera on carbon tetrachloride (CCl4)-induced hepatotoxicity in male rats. Frothy male Wistar rats were randomly divided into five groups inc...
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Ricinus communis Linn. (Euphorbiaceae) is a soft wooded tree widely prevalent throughout tropics regions of the world which have a warm temperature. In the Indian system of medicine, the leaves, roots and seed oil of this plant have been used for the treatment of inflammation and liver disorders for a lo...
متن کاملProtective Effect of Berberis integerrima Fruit Extract on Carbon-Tetrachloride Induced Hepatotoxicity in Rats
Background & Objective: Hepatoprotective effect of antioxidants such as flavnoids has been demonstrated. The aim of the present study was to assess the hepatoprotective effect of the methanolic extract of Berberis integerrima fruit (MEBIF) on carbon-tetrachloride (CCL4) induced hepatotoxicity in rats. Materials & Methods: Forty male rats were divided into 5 groups as follows: 1) normal, 2) toxi...
متن کاملHepatoprotective effect of Rosa canina fruit extract against carbon tetrachloride induced hepatotoxicity in rat
Objective: The present study was conducted to investigate the hepatoprotective activity of hydro-ethanolic fruit extract of Rosa canina (R. canina) against carbon tetrachloride (CCl4)-induced hepatotoxicity in rats. Methods: Male Wistar albino rats were randomly divided into six groups of 8 animals of each, including control, toxic (CCl4), R. canina 250, 500, and 750 mg/kg + CCl4 and R. canina ...
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ژورنال
عنوان ژورنال: Science and Technology Development Journal
سال: 2010
ISSN: 1859-0128
DOI: 10.32508/stdj.v13i3.2154